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Glutathione is a tripeptide molecule composed of three amino acids: cysteine, glutamine, and glycine

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Several molecules involved in the signal transduction processes, including small GTP-binding proteins and tyrosine kinases, such as c-Src, c-Yes, and protein kinase C (PKC), have been found to be localized at these tight junctions, presumably indicating their pivotal role in the maintenance of tight junction integrity 54,55

In MCAS, mast cells become hyperactive, degranulating in response to triggers that should not provoke a reaction

however, no response was observed in murine BMDMs (196)

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